| Award | Player | Team |
| Player of the Year | Brian Griese | Minnesota |
| Front Office Bowl MVP | Cory Boyd | New York (A) |
| Coach of the Year | Tom Luken | Minnesota |
| Legend of the Game | Marty Booker | San Diego |
| Offensive Player of the Year | Brian Griese | Minnesota |
| Defensive Player of the Year | Stephen Tulloch | Minnesota |
| Offensive Rookie of the Year | LeSean McCoy | New Orleans |
| Defensive Rookie of the Year | Clay Matthews | Pittsburgh |
| All-League First Team Quarterback | Brian Griese | Minnesota |
| All-League First Team Running Back | Chris Johnson | Philadelphia |
| All-League First Team Fullback | Lousaka Polite | Oakland |
| All-League First Team Tight End | Jared Cook | Miami |
| All-League First Team Wide Receiver | Steve Smith Sr. | New York (A) |
| All-League First Team Wide Receiver | Stevie Johnson | Minnesota |
| All-League First Team Center | Shaun O'Hara | St. Louis |
| All-League First Team Offensive Guard | Chris Chester | Washington |
| All-League First Team Offensive Guard | Fernando Velasco | Detroit |
| All-League First Team Offensive Tackle | King Dunlap | Minnesota |
| All-League First Team Offensive Tackle | Eric Winston | Denver |
| All-League First Team Punter | Brian Moorman | Cleveland |
| All-League First Team Kicker | Vince Joseph | Denver |
| All-League First Team Defensive End | Elvis Dumervil | Los Angeles |
| All-League First Team Defensive End | Kindal Moorehead | New Orleans |
| All-League First Team Defensive Tackle | Kyle Williams | New York (A) |
| All-League First Team Defensive Tackle | Mike Patterson | St. Louis |
| All-League First Team Inside Linebacker | Demarrio Williams | Green Bay |
| All-League First Team Outside Linebacker | Stephen Tulloch | Minnesota |
| All-League First Team Outside Linebacker | D'Qwell Jackson | Houston |
| All-League First Team Cornerback | Kelvin Hayden | Tennessee |
| All-League First Team Cornerback | Leon Hall | Cleveland |
| All-League First Team Safety | Ko Simpson | Kansas City |
| All-League First Team Safety | Vincent O'Field | Oakland |
| All-League Second Team Quarterback | Vince Young | Dallas |
| All-League Second Team Running Back | Adrian Peterson | Los Angeles |
| All-League Second Team Fullback | J.D. Runnels | Chicago |
| All-League Second Team Tight End | Jabari Holloway | San Francisco |
| All-League Second Team Wide Receiver | Braylon Edwards | San Francisco |
| All-League Second Team Wide Receiver | Matt Jones | Carolina |
| All-League Second Team Center | Robert Berry | Minnesota |
| All-League Second Team Offensive Guard | Steve Vallos | St. Louis |
| All-League Second Team Offensive Guard | Wilford Brown | Minnesota |
| All-League Second Team Offensive Tackle | John Tait | Buffalo |
| All-League Second Team Offensive Tackle | Bryant McKinnie | Dallas |
| All-League Second Team Punter | Rod Taylor | Detroit |
| All-League Second Team Kicker | Lamar Patton | San Diego |
| All-League Second Team Defensive End | Ray McDonald | New York (A) |
| All-League Second Team Defensive End | Justin Tuck | Indianapolis |
| All-League Second Team Defensive Tackle | Kevin Williams | Denver |
| All-League Second Team Defensive Tackle | Johnny Jolly | Pittsburgh |
| All-League Second Team Inside Linebacker | A.J. Hawk | Kansas City |
| All-League Second Team Outside Linebacker | Paul Posluszny | Cleveland |
| All-League Second Team Outside Linebacker | Sedric Dodge | Cincinnati |
| All-League Second Team Cornerback | Darrelle Revis | Chicago |
| All-League Second Team Cornerback | Marcus Trufant | New York (N) |
| All-League Second Team Safety | Chris Hope | Los Angeles |
| All-League Second Team Safety | Eric Weddle | Dallas |
| League's Fastest Man | Mario Manningham | Oakland |
| League's Strongest Man | Jeremy Zuttah | San Francisco |